Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline

Abstract Large-scale genomic studies focusing on the genetic contribution to human aging have mostly relied on cross-sectional data. With the release of longitudinally curated aging phenotypes by the UK Biobank (UKBB), it is now possible to study aging over time at genome-wide scale. In this work, w...

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Bibliographic Details
Main Authors: Tabea Schoeler, Jean-Baptiste Pingault, Zoltán Kutalik
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59383-0
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