Enhancement of enzymatic activity by biomolecular condensates through pH buffering

Abstract Biomolecular condensates can affect enzymatic reactions by locally changing not only concentrations of molecules but also their environment. Since protein conformations can differ between the dense and dilute phase, phase separation can particularly modulate enzymes characterized by a confo...

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Bibliographic Details
Main Authors: F. Stoffel, M. Papp, M. Gil-Garcia, A. M. Küffner, A. I. Benítez-Mateos, R. P. B. Jacquat, N. Galvanetto, L. Faltova, P. Arosio
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61013-8
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