A novel anti-NGF PEGylated Fab’ provides analgesia with lower risk of adverse effects

A novel anti-NGF PEGylated Fab’ provides analgesia with lower risk of adverse effects

Nerve growth factor (NGF) has emerged as a key driver of pain perception in several chronic pain conditions, including osteoarthritis (OA), and plays an important role in the generation and survival of neurons. Although anti-NGF antibodies improve pain control and physical function in patients with...

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Bibliographic Details
Main Authors: Yukari Koya, Hirotsugu Tanaka, Eiji Yoshimi, Nobuaki Takeshita, Shuji Morita, Hiroki Morio, Kanako Mori, Hiroshi Fushiki, Masazumi Kamohara
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:mAbs
Subjects:
NGF
PEGylated antibody
fab
arthritis
pain
placental transfer
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2022.2149055
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https://www.tandfonline.com/doi/10.1080/19420862.2022.2149055

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