Vaccinations in Pediatric Hematology and Oncology: Biologic Basis, Clinical Applications, and Perspectives

Vaccinations in Pediatric Hematology and Oncology: Biologic Basis, Clinical Applications, and Perspectives

Children with hemato-oncological diseases represent a heterogeneous population at heightened risk for vaccine-preventable diseases. Their immunosuppressed state reduces vaccine efficacy and raises safety concerns regarding live attenuated vaccines due to the risk of viral reactivation. The immunolog...

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Main Authors: Baldassarre Martire, Alessandra Beni, Maria Felicia Mastrototaro, Veronica Santilli, Giorgio Ottaviano, Davide Montin, Caterina Rizzo, Mayla Sgrulletti, Michele Miraglia del Giudice, Giorgio Costagliola, Viviana Moschese
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Vaccines
Subjects:
asplenia
chemotherapy
chimeric-antigen receptor T cells (CAR-T cells)
hematopoietic stem cell transplantation (HSCT)
immune reconstitution (IR)
immunization
Online Access:https://www.mdpi.com/2076-393X/13/4/397
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