TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis

BackgroundImmune cell infiltration into joint synovial tissue and promotion of the inflammatory response are important processes in rheumatoid arthritis (RA). This article delves into the crucial role of CD47 in these processes, as well as the mechanisms at both cellular and molecular levels.Methods...

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Bibliographic Details
Main Authors: Jialiang Hu, Xinmin Wang, Chuang Ge, Weiyan Qi, Zeqing Li, Yaoyao Wang, Wenting Lai, Wei Ji, Hanmei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1524304/full
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