The role of HDAC2 inhibition in cardioprotection against doxorubicin-induced myocardial injury

IntroductionThe molecular mechanisms underlying cardioprotection against doxorubicin (DOX)-induced myocardial injury are poorly understood. Histone deacetylase 2 (HDAC2) plays a significant role in oxidative stress, apoptosis, and mitochondrial dysfunction and is implicated in many human diseases, T...

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Bibliographic Details
Main Authors: Jinsha Liu, Wenwen Fu, Xue Wang, Zuowen Liang, Fanbo Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1557119/full
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