Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments

Diabetes-related cognitive impairment is increasingly recognized as a significant complication, profoundly impacting patients’ quality of life. This review aims to examine the pathophysiological mechanisms, clinical manifestations, risk factors, assessment and diagnosis, management strategies, and f...

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Main Authors: Yu Xueting, He Huimei, Wen Jie, Xu Xiuyuan, Ruan Zhaojuan, Hu Rui, Wang Fang, Ju Haibing
Format: Article
Language:English
Published: De Gruyter 2025-01-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2024-1091
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author Yu Xueting
He Huimei
Wen Jie
Xu Xiuyuan
Ruan Zhaojuan
Hu Rui
Wang Fang
Ju Haibing
author_facet Yu Xueting
He Huimei
Wen Jie
Xu Xiuyuan
Ruan Zhaojuan
Hu Rui
Wang Fang
Ju Haibing
author_sort Yu Xueting
collection DOAJ
description Diabetes-related cognitive impairment is increasingly recognized as a significant complication, profoundly impacting patients’ quality of life. This review aims to examine the pathophysiological mechanisms, clinical manifestations, risk factors, assessment and diagnosis, management strategies, and future research directions of cognitive impairment in diabetes.
format Article
id doaj-art-1cfd6b489dc945a4b5eb1f3718d7d0d1
institution Kabale University
issn 2391-5463
language English
publishDate 2025-01-01
publisher De Gruyter
record_format Article
series Open Medicine
spelling doaj-art-1cfd6b489dc945a4b5eb1f3718d7d0d12025-01-20T11:09:04ZengDe GruyterOpen Medicine2391-54632025-01-0120162754810.1515/med-2024-1091Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatmentsYu Xueting0He Huimei1Wen Jie2Xu Xiuyuan3Ruan Zhaojuan4Hu Rui5Wang Fang6Ju Haibing7Endocrine Department, 920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650000, Yunnan, ChinaEndocrine Department, 920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650000, Yunnan, ChinaExecutive Ward Department, 920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650000, Yunnan, ChinaEndocrine Department, 920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650000, Yunnan, ChinaEndocrine Department, 920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650000, Yunnan, ChinaDepartment of Hematology, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, 650000, Yunnan, ChinaExecutive Ward Department, 920th Hospital of Joint Logistics Support Force, PLA, Kunming, 650000, Yunnan, ChinaEndocrine Department, 920th Hospital of Joint Logistics Support Force, PLA, No. 212 Daguan Road, Xishan District, Kunming, 650000, Yunnan, ChinaDiabetes-related cognitive impairment is increasingly recognized as a significant complication, profoundly impacting patients’ quality of life. This review aims to examine the pathophysiological mechanisms, clinical manifestations, risk factors, assessment and diagnosis, management strategies, and future research directions of cognitive impairment in diabetes.https://doi.org/10.1515/med-2024-1091diabetescognitive dysfunctionhyperglycemiaexecutive functionneuroprotection
spellingShingle Yu Xueting
He Huimei
Wen Jie
Xu Xiuyuan
Ruan Zhaojuan
Hu Rui
Wang Fang
Ju Haibing
Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments
Open Medicine
diabetes
cognitive dysfunction
hyperglycemia
executive function
neuroprotection
title Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments
title_full Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments
title_fullStr Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments
title_full_unstemmed Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments
title_short Diabetes-related cognitive impairment: Mechanisms, symptoms, and treatments
title_sort diabetes related cognitive impairment mechanisms symptoms and treatments
topic diabetes
cognitive dysfunction
hyperglycemia
executive function
neuroprotection
url https://doi.org/10.1515/med-2024-1091
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AT ruanzhaojuan diabetesrelatedcognitiveimpairmentmechanismssymptomsandtreatments
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