Metabolic Characterization of Deceased Donor Kidneys Undergoing Hypothermic Machine Perfusion Before Transplantation Using 13C-enriched Glucose

Metabolic Characterization of Deceased Donor Kidneys Undergoing Hypothermic Machine Perfusion Before Transplantation Using 13C-enriched Glucose

Background. The provision of a metabolic substrate is one mechanism by which hypothermic machine perfusion (HMP) of kidneys provides clinical benefit. This study aimed to describe de novo metabolism in ex vivo human kidneys undergoing HMP before transplantation using 13C-labeled glucose as a metabol...

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Main Authors: Kamlesh Patel, PhD, Jay Nath, PhD, Thomas Smith, PhD, Tom Darius, PhD, Alpesh Thakker, PhD, Sarah Dimeloe, PhD, Nicholas Inston, PhD, Andrew Ready, MD, Christian Ludwig, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2025-01-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001736
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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001736

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