The role of autoantibodies in bridging obesity, aging, and immunosenescence

The role of autoantibodies in bridging obesity, aging, and immunosenescence

Abstract Antibodies are essential to immune homeostasis due to their roles in neutralizing pathogenic agents. However, failures in central and peripheral checkpoints that eliminate autoreactive B cells can undermine self-tolerance and generate autoantibodies that mistakenly target self-antigens, lea...

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Bibliographic Details
Main Authors: Taylor R. Valentino, Nan Chen, Priya Makhijani, Saad Khan, Shawn Winer, Xavier S. Revelo, Daniel A. Winer
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Immunity & Ageing
Subjects:
Autoantibodies
Obesity
Aging
Immunosenescence
Chronic inflammation
Online Access:https://doi.org/10.1186/s12979-024-00489-2
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https://doi.org/10.1186/s12979-024-00489-2

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