Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism
Abstract Objective To assess refractive and visual outcomes of a spherical Implantable Collamer Lens (ICL) followed by planned postoperative adjunctive laser-assisted in situ keratomileusis (LASIK) in the treatment of high compound hyperopic astigmatism. Methods In this prospective, multi-center, mu...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
|
| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12886-024-03828-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585897282895872 |
|---|---|
| author | Daniel Q. Li Mathieu Gauvin Guillermo Rocha Pierre Trottier Louis Racine Avi Wallerstein |
| author_facet | Daniel Q. Li Mathieu Gauvin Guillermo Rocha Pierre Trottier Louis Racine Avi Wallerstein |
| author_sort | Daniel Q. Li |
| collection | DOAJ |
| description | Abstract Objective To assess refractive and visual outcomes of a spherical Implantable Collamer Lens (ICL) followed by planned postoperative adjunctive laser-assisted in situ keratomileusis (LASIK) in the treatment of high compound hyperopic astigmatism. Methods In this prospective, multi-center, multi-surgeon, single-arm trial, eyes with ≥ 3.50 D hyperopia and ≥ 2.00 D of astigmatism underwent surgery receiving a spherical Implantable Collamer Lens (ICL) followed by a planned adjunctive LASIK postoperatively. Outcomes measures included postoperative uncorrected (UDVA) and corrected distance visual acuity (CDVA), manifest refraction, spherical (SEQ) and defocus equivalent (DEQ), efficacy index, safety index, and astigmatism vector analyses. Results 48 eyes had a mean sphere of 6.18 ± 1.35 D and mean cylinder of 2.69 ± 0.89 D preoperatively. After ICL and LASIK, 94% of eyes achieved a UDVA within 1 line of preoperative CDVA. Efficacy and safety indices were 0.94 ± 0.13 and 1.00 ± 0.13, respectively. We obtained near-to-emmetropia SEQ postoperatively (mean − 0.03 ± 0.43D), and the scatterplot of attempted versus achieved refractive correction revealed a predictable procedure (R2 = 0.89). 93.8% and 100% of eyes achieved target SEQ within 0.75 and 1.00 D. 87.5% and 100% of eyes were within 0.50 and 0.75 D of intended plano cylinder. Conclusion Spherical ICL with postoperative adjunctive LASIK was safe with good early visual and refractive outcomes. The combined modality is a promising approach to treating high compound hyperopic astigmatism where toric hyperopic ICL is not available. Trial registration This trial was retrospectively registered on ClinicalTrials.gov with the trial registration number NCT06742541. |
| format | Article |
| id | doaj-art-1cc7319bc410451ebb71f4d26f570c9c |
| institution | Kabale University |
| issn | 1471-2415 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj-art-1cc7319bc410451ebb71f4d26f570c9c2025-01-26T12:21:13ZengBMCBMC Ophthalmology1471-24152025-01-012511710.1186/s12886-024-03828-5Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatismDaniel Q. Li0Mathieu Gauvin1Guillermo Rocha2Pierre Trottier3Louis Racine4Avi Wallerstein5Department of Ophthalmology and Visual Sciences, McGill UniversityDepartment of Ophthalmology and Visual Sciences, McGill UniversityDepartment of Ophthalmology and Visual Sciences, McGill UniversityDepartment of Surgery, University of SherbrookeDepartment of Ophthalmology, University of MontrealDepartment of Ophthalmology and Visual Sciences, McGill UniversityAbstract Objective To assess refractive and visual outcomes of a spherical Implantable Collamer Lens (ICL) followed by planned postoperative adjunctive laser-assisted in situ keratomileusis (LASIK) in the treatment of high compound hyperopic astigmatism. Methods In this prospective, multi-center, multi-surgeon, single-arm trial, eyes with ≥ 3.50 D hyperopia and ≥ 2.00 D of astigmatism underwent surgery receiving a spherical Implantable Collamer Lens (ICL) followed by a planned adjunctive LASIK postoperatively. Outcomes measures included postoperative uncorrected (UDVA) and corrected distance visual acuity (CDVA), manifest refraction, spherical (SEQ) and defocus equivalent (DEQ), efficacy index, safety index, and astigmatism vector analyses. Results 48 eyes had a mean sphere of 6.18 ± 1.35 D and mean cylinder of 2.69 ± 0.89 D preoperatively. After ICL and LASIK, 94% of eyes achieved a UDVA within 1 line of preoperative CDVA. Efficacy and safety indices were 0.94 ± 0.13 and 1.00 ± 0.13, respectively. We obtained near-to-emmetropia SEQ postoperatively (mean − 0.03 ± 0.43D), and the scatterplot of attempted versus achieved refractive correction revealed a predictable procedure (R2 = 0.89). 93.8% and 100% of eyes achieved target SEQ within 0.75 and 1.00 D. 87.5% and 100% of eyes were within 0.50 and 0.75 D of intended plano cylinder. Conclusion Spherical ICL with postoperative adjunctive LASIK was safe with good early visual and refractive outcomes. The combined modality is a promising approach to treating high compound hyperopic astigmatism where toric hyperopic ICL is not available. Trial registration This trial was retrospectively registered on ClinicalTrials.gov with the trial registration number NCT06742541.https://doi.org/10.1186/s12886-024-03828-5Implantable collamer lensLASIKHyperopic astigmatism |
| spellingShingle | Daniel Q. Li Mathieu Gauvin Guillermo Rocha Pierre Trottier Louis Racine Avi Wallerstein Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism BMC Ophthalmology Implantable collamer lens LASIK Hyperopic astigmatism |
| title | Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism |
| title_full | Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism |
| title_fullStr | Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism |
| title_full_unstemmed | Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism |
| title_short | Spherical implantable collamer lens with postoperative adjunctive LASIK in the treatment of high compound hyperopic astigmatism |
| title_sort | spherical implantable collamer lens with postoperative adjunctive lasik in the treatment of high compound hyperopic astigmatism |
| topic | Implantable collamer lens LASIK Hyperopic astigmatism |
| url | https://doi.org/10.1186/s12886-024-03828-5 |
| work_keys_str_mv | AT danielqli sphericalimplantablecollamerlenswithpostoperativeadjunctivelasikinthetreatmentofhighcompoundhyperopicastigmatism AT mathieugauvin sphericalimplantablecollamerlenswithpostoperativeadjunctivelasikinthetreatmentofhighcompoundhyperopicastigmatism AT guillermorocha sphericalimplantablecollamerlenswithpostoperativeadjunctivelasikinthetreatmentofhighcompoundhyperopicastigmatism AT pierretrottier sphericalimplantablecollamerlenswithpostoperativeadjunctivelasikinthetreatmentofhighcompoundhyperopicastigmatism AT louisracine sphericalimplantablecollamerlenswithpostoperativeadjunctivelasikinthetreatmentofhighcompoundhyperopicastigmatism AT aviwallerstein sphericalimplantablecollamerlenswithpostoperativeadjunctivelasikinthetreatmentofhighcompoundhyperopicastigmatism |