ZHX2 inhibits diabetes-induced liver injury and ferroptosis by epigenetic silence of YTHDF2

Abstract Objective Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common complication of type 2 diabetes mellitus (DM). The transcription factor zinc fingers and homeoboxes 2 (ZHX2) has been implicated in the pathogenesis of chronic liver diseases, yet its precise role and und...

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Bibliographic Details
Main Authors: Wei Meng, Linghua Li
Format: Article
Language:English
Published: Nature Publishing Group 2025-02-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-025-00355-0
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