A Case of Congenital Hypotonia and Developmental Delay in an Individual with a De Novo Variant Outside of the Canonical HX-Motif of ATN1

We present a case of a 4-year-old female with a de novo heterozygous variant in the ATN1 gene. The whole exome sequencing was performed on the patient and her parents, and a likely pathogenic, de novo variant was identified in exon 5 of the ATN1 gene. There are two well-documented conditions associa...

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Bibliographic Details
Main Authors: Elizaveta Makarova, Nicole R. Legro, Ermal Aliu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Genetics
Online Access:http://dx.doi.org/10.1155/2023/1581876
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