Peroxidase-like Activity of G-Quadruplex/Hemin Complexes for Colorimetric Nucleic Acid Analysis: Loop and Flanking Sequences Affect Signal Intensity

Peroxidase-like Activity of G-Quadruplex/Hemin Complexes for Colorimetric Nucleic Acid Analysis: Loop and Flanking Sequences Affect Signal Intensity

<b>Background/Objectives</b>: Some G-quadruplex (G4)-forming nucleic acid sequences bind a hemin cofactor to enhance its peroxidase-like activity. This has been implemented in a variety of bioanalytical assays benefiting from analyte-dependent peroxidation of a chromogenic organic substr...

Full description

Saved in:
Bibliographic Details
Main Authors: Ryan P. Connelly, Valentina Fonseca, Yulia V. Gerasimova
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:DNA
Subjects:
G-quadruplexes
peroxidase-like deoxyribozymes
split probes
nucleic acid analysis
colorimetric assay
Online Access:https://www.mdpi.com/2673-8856/5/1/12
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2673-8856/5/1/12

Similar Items