Inflammation associated with monocyte/macrophage activation and recruitment corresponds with lethal outcome in a mouse model of Crimean-Congo haemorrhagic fever

Inflammation associated with monocyte/macrophage activation and recruitment corresponds with lethal outcome in a mouse model of Crimean-Congo haemorrhagic fever

Crimean-Congo haemorrhagic fever virus (CCHFV) causes human disease ranging from subclinical to a fatal haemorrhagic syndrome. Determinants of CCHF pathogenesis are largely unknown and animal models that recapitulate human disease are limited. A recently described mouse model uses a monoclonal antib...

Full description

Saved in:
Bibliographic Details
Main Authors: Teresa E. Sorvillo, Jana M. Ritter, Stephen R. Welch, JoAnn D. Coleman-McCray, Katherine A. Davies, Heather M. Hayes, Scott D. Pegan, Joel M. Montgomery, Éric Bergeron, Christina F. Spiropoulou, Jessica R. Spengler
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Crimean-Congo haemorrhagic fever virus
CCHF
Mice
Inflammation
Tropism
Macrophage activation
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2427782
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2024.2427782

Similar Items