3′ RACE Walking along a Large cDNA Employing Tiered Suppression PCR

Large genes present particular cloning difficulties, especially when expressed at relatively low levels. We describe a novel method, termed 3′ rapid amplification of cDNA ends (RACE) walking, for the rapid determination of unknown 3′ flanking sequence of a large cDNA. The technique is a derivative o...

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Bibliographic Details
Main Authors: Daniel J. Park, Andrew J. Pask, Marilyn B. Renfree, Jennifer A. Marshall Graves
Format: Article
Language:English
Published: Taylor & Francis Group 2003-04-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/03344st04
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