Causal impact of gut microbiota on five liver diseases: insights from mendelian randomization and single-cell RNA sequencing

Causal impact of gut microbiota on five liver diseases: insights from mendelian randomization and single-cell RNA sequencing

BackgroundLiver disease is among the top ten causes of death globally. With studies suggesting a link between gut microbiota (GM) and liver disease.MethodWe selected summary statistics data from the largest available whole-genome association study (n = 13,266) of GM by the MiBioGen consortium as the...

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Bibliographic Details
Main Authors: Na Li, Xuanyi Chen, Shuai Xiong, Yuxin Cheng, Jiali Deng, Junli Zhang, Fei Yu, Liyuan Hao, Shenghao Li, Xiaoyu Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Genetics
Subjects:
gut microbiota
five liver diseases
Prevotella
Mendelian randomization
SNPs
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1362139/full
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https://www.frontiersin.org/articles/10.3389/fgene.2024.1362139/full

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