Enhancing myelinogenesis through LIN28A rescues impaired cognition in PWMI mice
Abstract Background In premature newborn infants, preterm white matter injury (PWMI) causes motor and cognitive disabilities. Accumulating evidence suggests that PWMI may result from defected differentiation of oligodendrocyte precursor cells (OPCs) and impaired maturation of oligodendrocytes. Howev...
Saved in:
| Main Authors: | Xuan Wu, Zhechun Hu, Huimin Yue, Chao Wang, Jie Li, Yinxiang Yang, Zuo Luan, Liang Wang, Ying Shen, Yan Gu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Stem Cell Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13287-025-04267-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Effect of Tumor Necrosis Factor-α and Interleu-Kin-1β on the Restorative Properties of Human Oligodendrocyte Precursor Cells In Vitro
by: Zhaoyan Wang, et al.
Published: (2025-04-01) -
LIN28 upregulation in primary human T cells impaired CAR T antitumoral activity
by: Patricia Garcia-Rodriguez, et al.
Published: (2024-10-01) -
A Rat Model of Hyperoxia-Induced White Matter Injury
by: Yue Song, et al.
Published: (2025-05-01) -
Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injury
by: Meray Serdar, et al.
Published: (2025-02-01) -
LncRNA HOTAIR promotes aerobic glycolysis by recruiting Lin28 to induce inflammation and apoptosis in acute lung injury
by: Junjie Xie, et al.
Published: (2025-12-01)