Enhancing myelinogenesis through LIN28A rescues impaired cognition in PWMI mice

Enhancing myelinogenesis through LIN28A rescues impaired cognition in PWMI mice

Abstract Background In premature newborn infants, preterm white matter injury (PWMI) causes motor and cognitive disabilities. Accumulating evidence suggests that PWMI may result from defected differentiation of oligodendrocyte precursor cells (OPCs) and impaired maturation of oligodendrocytes. Howev...

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Bibliographic Details
Main Authors: Xuan Wu, Zhechun Hu, Huimin Yue, Chao Wang, Jie Li, Yinxiang Yang, Zuo Luan, Liang Wang, Ying Shen, Yan Gu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Stem Cell Research & Therapy
Subjects:
Preterm white matter injury
LIN28A
Oligodendrocyte
Oligodendrocyte precursor cells
Online Access:https://doi.org/10.1186/s13287-025-04267-9
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https://doi.org/10.1186/s13287-025-04267-9

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