Changes in Angiogenesis and Bone Turnover Markers in Patients with Gaucher Disease Developing Osteonecrosis

Changes in Angiogenesis and Bone Turnover Markers in Patients with Gaucher Disease Developing Osteonecrosis

<b>Background/Objectives</b>: Patients with Gaucher disease have a high risk of bone disease, with osteonecrosis representing the most debilitating complication. The pathogenesis of osteonecrosis has not been fully elucidated yet, and there is an unmet need for predictive biomarkers of b...

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Bibliographic Details
Main Authors: Simona D’Amore, Kenneth Eric Poole, Uma Ramaswami, Derralynn Hughes, Kathleen Page, Antonio Giovanni Solimando, Angelo Vacca, Timothy Martin Cox, Patrick Deegan
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Metabolites
Subjects:
Gaucher disease
osteonecrosis
biomarker
osteopontin
matrix metalloproteinases
vascular endothelial growth factor
Online Access:https://www.mdpi.com/2218-1989/14/11/601
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