Predicting clozapine-induced adverse drug reaction biomarkers using machine learning
Abstract Clozapine is an atypical antipsychotic used for patients with treatment-resistant schizophrenia. This drug has serious adverse drug reactions (ADRs), including the risk of severe neutropenia (agranulocytosis). Patients who could benefit from clozapine may not be administered it due to conce...
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| Main Authors: | John-Paul Cooper, Pierre Chue, Arno G. Siraki, Lusine Tonoyan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-09472-3 |
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