Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses.

The molecular details underlying the time-dependent assembly of protein complexes in cellular networks, such as those that occur during differentiation, are largely unexplored. Focusing on the calcium-induced differentiation of primary human keratinocytes as a model system for a major cellular reorg...

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Bibliographic Details
Main Authors: Kiana Toufighi, Jae-Seong Yang, Nuno Miguel Luis, Salvador Aznar Benitah, Ben Lehner, Luis Serrano, Christina Kiel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004256
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