Pharmacogenetic aspects of the effectiveness of nonsteroidal anti-inflammatory drugs and opioids for postoperative pain management in patients after total joint arthroplasty

Pharmacogenetic aspects of the effectiveness of nonsteroidal anti-inflammatory drugs and opioids for postoperative pain management in patients after total joint arthroplasty

Objective: to study the possible relationship between genetic, clinical, laboratory, demographic data and the average level of pain postoperatively, the need for opioid analgesics in patients who underwent total knee or hip arthroplasty.Materials and methods. The study included 61 patients who under...

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Main Authors: A. S. Zhiryakova, N. P. Denisenko, S. N. Tuchkova, A. S. Petrukhina, A. V. Kryukov, I. V. Sychev, K. B. Mirzaev, O. V. Averkov, V. I. Vechorko, E. O. Filatov, D. A. Sychev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-12-01
Series:Современная ревматология
Subjects:
arthroplasty
postoperative pain
pharmacokinetics
nsaids
opioid analgesics
Online Access:https://mrj.ima-press.net/mrj/article/view/1733
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