High-Dose Tranexamic Acid Enhances Circulating Neutrophil Extracellular Traps and Thrombus in Thrombosis Mouse Model

<b>Background/Objectives</b>: Tranexamic acid (TXA) reduces mortality in patients with massive hemorrhage by inhibiting fibrinolysis. However, it is associated with an increased risk of thrombosis. The activation of neutrophil extracellular traps (NETs) has been implicated in the formati...

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Bibliographic Details
Main Authors: Jung-Wook Song, Eun-Hye Seo, Un Yung Choi, Chung-Sik Oh, Aram Kim, Keeho Song, Seung-Hyun Lee, Jin Kook Kim
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/6/1284
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