Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses
Highlights Recombinant avipoxviruses as putative recombinant vaccines against MPXV. Different prime–boost regimens to improve immunization against orthopoxviruses. Mucosal and intramuscular immunization to enhance the humoral and neutralizing immune response.
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| Main Authors: | Antonia Radaelli, Carlo Zanotto, Chiara Brambilla, Tommaso Adami, Francesca Paolini, Aldo Venuti, Adriana Manuka, Irsida Mehmeti, Carlo De Giuli Morghen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | Virology Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12985-024-02534-4 |
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