Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma

Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma

Abstract Background The clinical significance of circulating tumor cell (CTC) clusters in highly metastatic tumors hasn’t yet been revealed. Here, we demonstrated the diagnostic and prognostic value of CTC clusters in neuroblastoma (NB) which is the most prevalent childhood extracranial solid tumor....

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Main Authors: Huanli Xu, Nianhua Cao, Wenyan Dai, Caiwei Sima, Meng Yi, Senmin Chen, Xiaowen Chen, Chao Liu, Uet Yu, Huiping Lang, Zhedie Zhou, Nanlin Yang, Chunjing Wang, Xianping Jiang, Yungen Gan, Jianyao Wang, Yuanxiang Wang, Nuaner Yao, Lidan Xiao, Qing Zhang, Junjie Sun, Zhou Lin, Gongwei Zhang, Jiayue Zhang, Hongtao Feng, Jianming Song, Sixi Liu, Zongbin Liu, Feiqiu Wen, Xiuli Yuan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Circulating tumor cell
Circulating tumor cell cluster
Microfluidic chip
Neuroblastoma
Liquid biopsy
Online Access:https://doi.org/10.1186/s12885-025-14448-7
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https://doi.org/10.1186/s12885-025-14448-7

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