Novel Anthraquinone Derivatives and Their Complexes with Metal Ions with Anticancer Activity: Structure/Redox and Chelation Activity Correlations

Novel Anthraquinone Derivatives and Their Complexes with Metal Ions with Anticancer Activity: Structure/Redox and Chelation Activity Correlations

<b>Background/Objectives:</b> Some specific anthraquinone derivatives (AQs) are known to be used widely as effective chemotherapeutic agents in the treatment of cancer. However, their fundamental shortcoming is the high rate of cardiotoxicity observed in treated patients, which is though...

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Bibliographic Details
Main Authors: Olga Yu. Selyutina, Maya A. Ul’yanova, Olga A. Chinak, Viktor A. Timoshnikov, Lidiya G. Fedenok, Alexander A. Stepanov, Vadim V. Yanshole, Leonid V. Kulik, Sergey F. Vasilevsky, Nikolay E. Polyakov, George J. Kontoghiorghes
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
anthraquinones
quinones
chelation
metal complexes
iron complexes
copper complexes
Online Access:https://www.mdpi.com/1424-8247/17/12/1717
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