The multiple mechanisms and modes of cell death after acetaminophen overdose

Acetaminophen (APAP)-induced liver injury and acute liver failure is a significant clinical problem worldwide; in addition, APAP overdoses in animals or in cell culture are used as popular models to study drug-induced liver injury mechanisms and test therapeutic interventions. Early assumptions that...

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Bibliographic Details
Main Authors: Hartmut Jaeschke, Anup Ramachandran
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-04-01
Series:Exploration of Digestive Diseases
Subjects:
Online Access:https://www.explorationpub.com/uploads/Article/A100569/100569.pdf
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