Preoperative inflammatory pain exacerbates postoperative pain and neurocognitive impairment

Preoperative inflammatory pain exacerbates postoperative pain and neurocognitive impairment

Aims: Many studies have shown that postoperative pain aggravates perioperative neurocognitive disorder (PND). In this study we aimed to clarify the effect of preoperative inflammatory pain on postoperative pain and cognitive function. Methods: We established the inflammatory pain model by injected c...

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Bibliographic Details
Main Authors: Hui Yuan, Daofan Sun, Bo Lu, Bo Meng, Rongjun Liu, Ruichun Wang, Xiuzhong Xing, Yiqin Ji, Qianyu Ming, Qiusheng Wang, Junping Chen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:IBRO Neuroscience Reports
Subjects:
Pain
Perioperative neurocognitive disorder
α7nAChR
HMGB1
Neuroinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000442
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http://www.sciencedirect.com/science/article/pii/S2667242125000442

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