Antimicrobial resistance and phylogenetic lineages of KPC-2-producing blood-borne Klebsiella pneumoniae subsp. pneumoniae from Kolkata, India during 2015–2024: Emergence of Klebsiella pneumoniae subsp. pneumoniae with blaKPC-2, blaNDM, and blaOXA-48-like triple carbapenemases

Antimicrobial resistance and phylogenetic lineages of KPC-2-producing blood-borne Klebsiella pneumoniae subsp. pneumoniae from Kolkata, India during 2015–2024: Emergence of Klebsiella pneumoniae subsp. pneumoniae with blaKPC-2, blaNDM, and blaOXA-48-like triple carbapenemases

ABSTRACT In view of insufficient data on the epidemiology and genomics of blaKPC-2 producing Klebsiella pneumoniae subsp. pneumoniae (KPC-2 Kpn) from India, this study, first of its kind, was conducted to characterize blood-borne KPC-2 Kpn isolates according to their resistome, plasmid types, and ge...

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Main Authors: Gourab Halder, Bhaskar Narayan Chaudhuri, Balaji Veeraraghavan, Priyanka Denny, Paulami Dutta, Mandira Chakraborty, Ujjwayini Ray Khan, Shelley Sharma Ganguly, Subhranshu Mandal, Yesha Parasmani Upadhyaya, Bedobroto Biswas, Arindam Chakraborty, Sourav Maiti, Himadri Mondal, Saikat Pal, Shanta Dutta
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
triple carbapenemases
blaKPC-2
ceftazidime-avibactam resistant blaKPC-2
blaKPC-2 with blaNDM
blaKPC-2 with blaOXA-48-like-variants
sepsis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00126-25
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