Targeting oncofetal fibronectin and neuropilin-1 in solid tumors with PL2 peptide

Targeting oncofetal fibronectin and neuropilin-1 in solid tumors with PL2 peptide

Abstract To improve the precision and selectivity of anticancer therapies, affinity ligands targeting molecules of the malignancy-associated vascular signature are used. One such target is Fibronectin Extra Domain-B (Fn-EDB), an oncofetal splice variant of a major extracellular matrix protein (Fn),...

Full description

Saved in:
Bibliographic Details
Main Authors: Prakash Lingasamy, Allan Tobi, Kaarel Kurm, Olav Tammik, Tambet Teesalu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Fibronectin extra Domain-B (Fn-EDB)
Neuropilin-1 (NRP-1)
Extracellular matrix
Homing peptide
In vivo phage display
Glioblastoma
Online Access:https://doi.org/10.1038/s41598-025-11299-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-11299-x

Similar Items