Molecular Mechanisms of Cellular Senescence in Age-Related Endometrial Dysfunction

Molecular Mechanisms of Cellular Senescence in Age-Related Endometrial Dysfunction

The endometrium is essential for reproductive function, supporting implantation and pregnancy through mechanisms such as hormonal responsiveness, immune regulation, and tissue regeneration. Aging disrupts these processes, with cellular senescence—marked by irreversible cell cycle arrest due to DNA d...

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Bibliographic Details
Main Authors: Hiroshi Kobayashi, Mai Umetani, Miki Nishio, Hiroshi Shigetomi, Shogo Imanaka, Hiratsugu Hashimoto
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
AMPK
autophagy
endometrium
mTOR
p53
senescence
Online Access:https://www.mdpi.com/2073-4409/14/12/858
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