A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression

A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression

Hypertension-related Depression (HD) is a complex mental disorder that exerts a significant negative impact on patients’ quality of life. Previous studies have demonstrated that damages to vascular endothelial and hippocampus are the primary pathological features in HD rats. Under hypertensive condi...

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Bibliographic Details
Main Authors: Hongxia Zhao, Lingge Huang, Jian Liu, Min Feng, Yeqian Liu, Hong Li, Shan Gong, Chunming Chen, Shuiqing Zeng, Weiqiong Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
co-culture
hypertension
depression
inflammation
TLR4
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1553309/full
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https://www.frontiersin.org/articles/10.3389/fncel.2025.1553309/full

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