Endogenous opioid antagonism in physiological experimental pain models: a systematic review.

Opioid antagonists are pharmacological tools applied as an indirect measure to detect activation of the endogenous opioid system (EOS) in experimental pain models. The objective of this systematic review was to examine the effect of mu-opioid-receptor (MOR) antagonists in placebo-controlled, double-...

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Bibliographic Details
Main Authors: Mads U Werner, Manuel P Pereira, Lars Peter H Andersen, Jørgen B Dahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125887
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