Bempedoic Acid, the First-in-Class Oral ATP Citrate Lyase Inhibitor with Hypocholesterolemic Activity: Clinical Pharmacology and Drug–Drug Interactions

Bempedoic Acid, the First-in-Class Oral ATP Citrate Lyase Inhibitor with Hypocholesterolemic Activity: Clinical Pharmacology and Drug–Drug Interactions

Bempedoic acid is a new drug that improves the control of cholesterol levels, either as monotherapy or in combination with existing lipid-lowering therapies, and shows clinical efficacy in cardiovascular disease patients. Thus, patients with comorbidities and under multiple therapies may be eligible...

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Bibliographic Details
Main Authors: Nicola Ferri, Elisa Colombo, Alberto Corsini
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceutics
Subjects:
drug–drug interactions
bempedoic acid
statins
cytochrome P450
P-gp
organic anion transporter 2
Online Access:https://www.mdpi.com/1999-4923/16/11/1371
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https://www.mdpi.com/1999-4923/16/11/1371

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