Identification of a novel small-molecule inhibitor of the HIV-1 reverse transcriptase activity with a non-nucleoside mode of action

Abstract Background Human immunodeficiency virus-1 (HIV-1) is the causative agent of acquired immunodeficiency syndrome, which is a major global health problem. Although combination antiretroviral therapy (cART) successfully expands the lifespan of HIV-1-infected patients, long-term cART often incre...

Full description

Saved in:
Bibliographic Details
Main Authors: Kyung-Lee Yu, YoungHyun Shin, Dong-Eun Kim, Jeong-Ah Kim, Jeong-Eun Kang, Pooja Singh, Keun Woo Lee, Chul Min Park, Hojin Kwon, Sunwoo Kim, Songmee Bae, Cheol-Hee Yoon
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-025-02680-3
Tags: Add Tag
No Tags, Be the first to tag this record!