Depression as a risk factor for Alzheimer's disease: A human post-mortem study.

Depression is associated with persistent low mood. In mid to late life, it has been identified as a risk factor for Alzheimer's disease (AD) with evidence that depression might be an early manifestation of AD. Although the underlying mechanisms by which depression enhances AD development remain...

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Bibliographic Details
Main Authors: Mizuki Morisaki, Farnoosh Rezaali, Laurie C Lau, Delphine Boche, Golam M Khandaker, Gustavo Turecki, Lindsey I Sinclair
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320561
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