Efficacy and safety of GLP-1 receptor agonists on weight management and metabolic parameters in PCOS women: a meta-analysis of randomized controlled trials

Efficacy and safety of GLP-1 receptor agonists on weight management and metabolic parameters in PCOS women: a meta-analysis of randomized controlled trials

Abstract This meta-analysis aimed to evaluate the efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) when compared to metformin and placebo in the management of body weight, glucose homeostasis and hormone levels in women polycystic ovary syndrome (PCOS). A systematic search...

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Bibliographic Details
Main Authors: Shike Lin, Yan Deng, Jing Huang, Meiyan Li, Suren Rao Sooranna, Minzhen Qin, Bing Tan
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Polycystic ovary syndrome
GLP-1 receptor agonists
Anthropometric measurement
Glucose homeostasis
Metabolic outcomes
Meta-analysis of RCTs
Online Access:https://doi.org/10.1038/s41598-025-99622-4
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https://doi.org/10.1038/s41598-025-99622-4

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