M1 and M2 macrophages markers are alternately expressed during periapical lesion development

M1 and M2 macrophages markers are alternately expressed during periapical lesion development

Abstract Background This study evaluated the altered expression levels of genes and cytokines associated with M1 and M2 macrophages during the development of periapical lesion (PL). Methodology PL was induced in the lower first molars of 96 mice. After the experimental periods of two, seven, 14,...

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Main Authors: Carolina Maschietto PUCINELLI, Paulo NELSON-FILHO, Marília Pacífico LUCISANO, Jorge Esquiche LEÓN, Lúcia Helena FACCIOLI, Carlos Arterio SORGI, Clara Marina Pereira Cavalcanti SILVA, Lea Assed Bezerra da SILVA, Raquel Assed Bezerra da SILVA
Format: Article
Language:English
Published: University of São Paulo 2025-06-01
Series:Journal of Applied Oral Science
Subjects:
Macrophage polarization
Periapical lesion
Microscopic evaluation
Gene expression
Cytokines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572025000100430&lng=en&tlng=en
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