Resolution of oncogene-induced senescence markers in HPV-infected cervical cancer tissue

Resolution of oncogene-induced senescence markers in HPV-infected cervical cancer tissue

Abstract Background Oncogene-Induced Senescence (OIS) is a form of senescence that occurs as a consequence of oncogenic overstimulation and possibly infection by oncogenic viruses. Whether senescence plays a role in the pathogenesis of cervical cancer (CC) is not well understood. Moreover, whether c...

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Main Authors: Ashraf I. Khasawneh, Sofian Al Shboul, Nisreen Himsawi, Amani Al Rousan, Nisreen Abu Shahin, Mohammed El-Sadoni, Ahmad Alhesa, Ala’ Abu Ghalioun, Suzan Khawaldeh, Bayan Shawish, Salem Abu Mahfouz, Mais Al-Shayeb, Shatha Abo Dawoud, Raghad Tlilan, Mohammad Nuseir, Moureq R. Alotaibi, Ola Abu Al Karsaneh, Fida Asali, Marcos Yébenes Mayordomo, Raghda Barham, Rame Khasawneh, Tareq Saleh
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Oncogene-induced senescence
SASP
Cervix
CIN, cancer
HPV
Online Access:https://doi.org/10.1186/s12885-025-13499-0
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https://doi.org/10.1186/s12885-025-13499-0

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