mGluR5-mediated astrocytes hyperactivity in the anterior cingulate cortex contributes to neuropathic pain in male mice

mGluR5-mediated astrocytes hyperactivity in the anterior cingulate cortex contributes to neuropathic pain in male mice

Abstract Astrocytes regulate synaptic transmission in healthy and pathological conditions, but their involvement in modulating synaptic transmission in chronic pain is unknown. Our study demonstrates that astrocytes in the anterior cingulate cortex (ACC) exhibit abnormal calcium signals and induce t...

Full description

Saved in:
Bibliographic Details
Main Authors: Weida Shen, Fujian Chen, Yejiao Tang, Yulu Zhao, Linjing Zhu, Liyang Xiang, Li Ning, Wen Zhou, Yiran Chen, Liangxue Wang, Jing Li, Hui Huang, Ling-Hui Zeng
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07733-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s42003-025-07733-5

Similar Items