Botulinum toxin type-A effect as a preemptive treatment in a model of acute trigeminal pain: a pre-clinical double-blind and placebo-controlled study

Botulinum toxin type-A effect as a preemptive treatment in a model of acute trigeminal pain: a pre-clinical double-blind and placebo-controlled study

The purpose of this study was to investigate if botulinum neurotoxin type-A (BoNT/A) had a preemptive antinociceptive effect in a formalin-induced orofacial pain model (FT). To test this hypothesis, male Rattus norvegicus were injected with isotonic saline solution 0.9% or BoNT/A administered as a 4...

Full description

Saved in:
Bibliographic Details
Main Authors: Elcio Juliato Piovesan, Lucas da Silva Leite, Helio Ghizoni Teive, Pedro André Kowacs, Rogério Andrade Mulinari, Victor Radunz, Marco Utiumi, Helder Groenwold Campos, Lineu Cesar Werneck
Format: Article
Language:English
Published: Thieme Revinter Publicações 2011-02-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
dor orofacial
efeito antinociceptivo
toxina botulínica do tipo-A
tratamento preemptivo
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100012&lng=en&tlng=en
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100012&lng=en&tlng=en

Similar Items