Condition-controlled divergent trifluoroalkylation: a diversity-oriented synthesis strategy for efficient construction of CF3-decorated carbazole libraries
Abstract A condition-controlled divergent trifluoroalkylation strategy for carbazole derivatives has been developed via alkylation with trifluoropyruvate. Employing trifluoroacetic acid (TFA) promoter, FeCl3 catalyst, or AgSbF6 catalyst, a wide scope of mono-trifluoromethylated carbazolylethanols (2...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Chemistry |
| Online Access: | https://doi.org/10.1186/s13065-025-01536-9 |
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