A post-marketing surveillance study of dabrafenib and trametinib combination in Japanese patients with unresectable advanced or recurrent BRAF-mutated NSCLC

Abstract Combination therapy with dabrafenib and trametinib has been shown to improve response and survival outcomes in patients with BRAF V600E-mutated non–small cell lung cancer (NSCLC). However, safety and efficacy data in Japanese patients with unresectable NSCLC are limited in clinical trials....

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Bibliographic Details
Main Authors: Tomoaki Kaizuka, Ryohei Kurihara, Yuya Yokochi, Naoko Suenaga
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-07467-8
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