Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition

Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition

Abstract The peritoneum is the most common site of metastasis in advanced gastric cancer (GC), and the mechanisms underlying this process of gastric cancer peritoneal metastasis (GCPM) remain largely elusive. Mesothelial-mesenchymal transition (MMT) plays a crucial role in the progression of GCPM. I...

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Main Authors: Chao Dong, Yajing Zhou, Xiaochun Shen, Shuo Hu, Kaipeng Duan, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Pengbo Wang, Ye Han, Dongbao Li, Qiaoming Zhi, Jin Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07749-z
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https://doi.org/10.1038/s41419-025-07749-z

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