CO confers neuroprotection via activating the PERK-calcineurin pathway and inhibiting necroptosis

CO confers neuroprotection via activating the PERK-calcineurin pathway and inhibiting necroptosis

Abstract Neurodegenerative diseases, such as Parkinson’s disease (PD) and Alzheimer’s disease (AD), are marked by progressive neuronal loss. Regulated cell death programs (i.e., necroptosis) as well as homeostatic mechanisms (i.e., autophagy) can modulate disease pathogenesis. Low-dose carbon monoxi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jeongmin Park, LiHua Jin, Hyun-Chul Song, Yingqing Chen, Eun Young Jang, Gyu Hwan Park, Chae Ha Yang, Stefan W. Ryter, Jeong Woo Park, Min Zheng, Yeonsoo Joe, Hun Taeg Chung
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02530-9
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items