Spatial transcriptome analysis of myenteric plexus and intestinal epithelium of colon in patients with Parkinson’s disease

Abstract Alpha-synuclein (AS) accumulation is found in the nerve plexuses of the gastrointestinal tract in patients with Parknison’s disease (PD). Moreover, alterations in microbiome composition and its metabolites were confirmed in the colon of patients with PD. However, there has been no study tha...

Full description

Saved in:
Bibliographic Details
Main Authors: Chaewon Shin, Karoliina Eliisa Ruhno, Jung Hwan Shin, Sanha Hwang, Jasper Roldan Go, Minji Kang, Hyun Je Kim, Ji Hwan Moon, Han-Joon Kim
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-025-02047-3
Tags: Add Tag
No Tags, Be the first to tag this record!