Solvent-free and eco-friendly green protocol for N-Boc Protection of amines using picric acid as a catalyst
We have developed an environmentally conscious green protocol to protect amine functional groups in drug discovery and the total synthesis of biologically active natural products. This method utilizes di-tert-butyl dicarbonate ((Boc)2O) to protect aromatic and aliphatic amines, with readily availabl...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Tetrahedron Green Chem |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773223124000268 |
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