Chiral Recognition Mechanism of Benzyltetrahydroisoquinoline Alkaloids: Cyclodextrin-Mediated Capillary Electrophoresis, Chiral HPLC, and NMR Spectroscopy Study

Chiral Recognition Mechanism of Benzyltetrahydroisoquinoline Alkaloids: Cyclodextrin-Mediated Capillary Electrophoresis, Chiral HPLC, and NMR Spectroscopy Study

The tetrahydroisoquinoline skeleton is a pharmacologically significant core structure containing chiral centers, making enantiomeric separation crucial due to the potentially distinct biological effects of each enantiomer. In this study, laudanosine (<i>N</i>-methyl-tetrahydropapaverine)...

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Bibliographic Details
Main Authors: Erzsébet Várnagy, Gergő Tóth, Sándor Hosztafi, Máté Dobó, Ida Fejős, Szabolcs Béni
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
Subjects:
inclusion complexation
enantioseparation
enantiodiscrimination
laudanosine
tetrahydropapaverine
norlaudanosine
Online Access:https://www.mdpi.com/1420-3049/30/5/1125
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