MAST Kinases’ Function and Regulation: Insights from Structural Modeling and Disease Mutations

<b>Background/Objectives</b>: The MAST kinases are ancient AGC kinases associated with many human diseases, such as cancer, diabetes, and neurodevelopmental disorders. We set out to describe the origins and diversification of MAST kinases from a structural and bioinformatic perspective t...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael C. Lemke, Nithin R. Avala, Michael T. Rader, Stefan R. Hargett, Daniel S. Lank, Brandon D. Seltzer, Thurl E. Harris
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/13/4/925
Tags: Add Tag
No Tags, Be the first to tag this record!