HPV and head and neck cancer: A comprehensive review
Human papilloma virus (HPV) has historically been implicated in the etiopathogenesis of cervical cancers in females. However, in recent times, HPV has been found to be increasingly associated with cancers of the oral cavity especially with oropharyngeal carcinomas. The epidemiology of HPV positive c...
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Format: | Article |
Language: | English |
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Elsevier
2024-06-01
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Series: | Oral Oncology Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024002978 |
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author | Pallavi Taneja Monica C. Solomon |
author_facet | Pallavi Taneja Monica C. Solomon |
author_sort | Pallavi Taneja |
collection | DOAJ |
description | Human papilloma virus (HPV) has historically been implicated in the etiopathogenesis of cervical cancers in females. However, in recent times, HPV has been found to be increasingly associated with cancers of the oral cavity especially with oropharyngeal carcinomas. The epidemiology of HPV positive cancers is different than that of the HPV negative cases. Consequently, study of HPV has become the center of focus of many oral pathologists. The prognosis of HPV positive cancer is better and can be explained by several theories. The following is a narrative review of mechanism of oncogenesis by HPV, diagnosis, comparison of the prognosis and clinical features between HPV positive and negative cases, histological features and finally a brief overview of the management options of HPV positive cancers. |
format | Article |
id | doaj-art-1a7fcbaeaec24265bb738bd2618093cf |
institution | Kabale University |
issn | 2772-9060 |
language | English |
publishDate | 2024-06-01 |
publisher | Elsevier |
record_format | Article |
series | Oral Oncology Reports |
spelling | doaj-art-1a7fcbaeaec24265bb738bd2618093cf2025-01-09T06:16:19ZengElsevierOral Oncology Reports2772-90602024-06-0110100451HPV and head and neck cancer: A comprehensive reviewPallavi Taneja0Monica C. Solomon1Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India; Corresponding author. Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.Department of Oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India; Corresponding author.Human papilloma virus (HPV) has historically been implicated in the etiopathogenesis of cervical cancers in females. However, in recent times, HPV has been found to be increasingly associated with cancers of the oral cavity especially with oropharyngeal carcinomas. The epidemiology of HPV positive cancers is different than that of the HPV negative cases. Consequently, study of HPV has become the center of focus of many oral pathologists. The prognosis of HPV positive cancer is better and can be explained by several theories. The following is a narrative review of mechanism of oncogenesis by HPV, diagnosis, comparison of the prognosis and clinical features between HPV positive and negative cases, histological features and finally a brief overview of the management options of HPV positive cancers.http://www.sciencedirect.com/science/article/pii/S2772906024002978 |
spellingShingle | Pallavi Taneja Monica C. Solomon HPV and head and neck cancer: A comprehensive review Oral Oncology Reports |
title | HPV and head and neck cancer: A comprehensive review |
title_full | HPV and head and neck cancer: A comprehensive review |
title_fullStr | HPV and head and neck cancer: A comprehensive review |
title_full_unstemmed | HPV and head and neck cancer: A comprehensive review |
title_short | HPV and head and neck cancer: A comprehensive review |
title_sort | hpv and head and neck cancer a comprehensive review |
url | http://www.sciencedirect.com/science/article/pii/S2772906024002978 |
work_keys_str_mv | AT pallavitaneja hpvandheadandneckcanceracomprehensivereview AT monicacsolomon hpvandheadandneckcanceracomprehensivereview |