HPV and head and neck cancer: A comprehensive review

Human papilloma virus (HPV) has historically been implicated in the etiopathogenesis of cervical cancers in females. However, in recent times, HPV has been found to be increasingly associated with cancers of the oral cavity especially with oropharyngeal carcinomas. The epidemiology of HPV positive c...

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Main Authors: Pallavi Taneja, Monica C. Solomon
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Oral Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024002978
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author Pallavi Taneja
Monica C. Solomon
author_facet Pallavi Taneja
Monica C. Solomon
author_sort Pallavi Taneja
collection DOAJ
description Human papilloma virus (HPV) has historically been implicated in the etiopathogenesis of cervical cancers in females. However, in recent times, HPV has been found to be increasingly associated with cancers of the oral cavity especially with oropharyngeal carcinomas. The epidemiology of HPV positive cancers is different than that of the HPV negative cases. Consequently, study of HPV has become the center of focus of many oral pathologists. The prognosis of HPV positive cancer is better and can be explained by several theories. The following is a narrative review of mechanism of oncogenesis by HPV, diagnosis, comparison of the prognosis and clinical features between HPV positive and negative cases, histological features and finally a brief overview of the management options of HPV positive cancers.
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institution Kabale University
issn 2772-9060
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series Oral Oncology Reports
spelling doaj-art-1a7fcbaeaec24265bb738bd2618093cf2025-01-09T06:16:19ZengElsevierOral Oncology Reports2772-90602024-06-0110100451HPV and head and neck cancer: A comprehensive reviewPallavi Taneja0Monica C. Solomon1Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India; Corresponding author. Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.Department of Oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India; Corresponding author.Human papilloma virus (HPV) has historically been implicated in the etiopathogenesis of cervical cancers in females. However, in recent times, HPV has been found to be increasingly associated with cancers of the oral cavity especially with oropharyngeal carcinomas. The epidemiology of HPV positive cancers is different than that of the HPV negative cases. Consequently, study of HPV has become the center of focus of many oral pathologists. The prognosis of HPV positive cancer is better and can be explained by several theories. The following is a narrative review of mechanism of oncogenesis by HPV, diagnosis, comparison of the prognosis and clinical features between HPV positive and negative cases, histological features and finally a brief overview of the management options of HPV positive cancers.http://www.sciencedirect.com/science/article/pii/S2772906024002978
spellingShingle Pallavi Taneja
Monica C. Solomon
HPV and head and neck cancer: A comprehensive review
Oral Oncology Reports
title HPV and head and neck cancer: A comprehensive review
title_full HPV and head and neck cancer: A comprehensive review
title_fullStr HPV and head and neck cancer: A comprehensive review
title_full_unstemmed HPV and head and neck cancer: A comprehensive review
title_short HPV and head and neck cancer: A comprehensive review
title_sort hpv and head and neck cancer a comprehensive review
url http://www.sciencedirect.com/science/article/pii/S2772906024002978
work_keys_str_mv AT pallavitaneja hpvandheadandneckcanceracomprehensivereview
AT monicacsolomon hpvandheadandneckcanceracomprehensivereview